Introduction to Diagnostic Medical Parasitology
Plasmodium vivax
Ring
![](/.imaging/mte/default-theme/parasiteImage/dam/exercises/Exercise-for-plasmodia/pv_100_c.tif.jpg/jcr:content/pv_100_c.tif.jpg)
Ring
- Delicate ring
- RBC larger than normal
- Deformed
Growing trophozoite; Schüffner's dots
![](/.imaging/mte/default-theme/parasiteImage/dam/exercises/Exercise-for-plasmodia/pv_100_b.tif.jpg/jcr:content/pv_100_b.tif.jpg)
Growing trophozoite; Schüffner's dots
- Very amoeboid trophozoite
- Enlarged RBCs and deformed
- Schüffner's dots appear after 8-10 hours
Immature schizont
![](/.imaging/mte/default-theme/parasiteImage/dam/parasites/protozoa/malaria/plasmodium-vivax/P.vivax.Schizont.unreif.3.100x__006_001_004_006_002_002_002_.jpg0/jcr:content/P.vivax.Schizont.unreif.3.100x__006_001_004_006_002_002_002_.jpg)
![](/.imaging/mte/default-theme/parasiteImage/dam/parasites/protozoa/malaria/plasmodium-vivax/P.vivax.Schizont.unreif.5.100x__006_001_004_006_002_002_002_.jpg/jcr:content/P.vivax.Schizont.unreif.5.100x__006_001_004_006_002_002_002_.jpg)
Immature schizont
- Looks like a growing trophozoite with several chromatins
- The single merozoite is not yet defined
Mature schizont
![](/.imaging/mte/default-theme/parasiteImage/dam/parasites/protozoa/malaria/plasmodium-vivax/P.vivax.Schizont.7.100x__006_001_004_006_002_002_002_00___00.jpg/jcr:content/P.vivax.Schizont.7.100x__006_001_004_006_002_002_002_00___00.jpg)
Mature schizont
- Contains 12-24 merozoites
- Pigment in 1 or 2 clumps
- Peripheral or central
Ruptured schizont
![](/.imaging/mte/default-theme/parasiteImage/dam/parasites/protozoa/malaria/plasmodium-vivax/P.vivax.Schizont.5.100x__006_001_004_006_002_002_002_00___00.jpg/jcr:content/P.vivax.Schizont.5.100x__006_001_004_006_002_002_002_00___00.jpg)
Ruptured schizont
- RBCs membran ruptured and the merozoites (up to 24) are set free to infect new RBCs
Macrogametocyte
![](/.imaging/mte/default-theme/parasiteImage/dam/Virtual-Microscope/Excercises/Korrekte-Bilder/pv_100_n.tif.jpg/jcr:content/pv_100_n.tif.jpg)
Macrogametocyte
- Chromatin small
- Eccentric and dark red
- Cytoplasm homogeneous
- Blue
- Without vacuoles
- Pigment scattered
- Macrogametocyte fills the RBC
Microgametocyte
![](/.imaging/mte/default-theme/parasiteImage/dam/Virtual-Microscope/Excercises/Korrekte-Bilder/pv_100_g.tif.jpg/jcr:content/pv_100_g.tif.jpg)
Microgametocyte
- Chromatin mass larger than in microgametocyte
- Eccentric or central
- Diffuse
- Light red
Cytoplasm from light blue to pink
- Pigment finer
- Scattered
- Microgametocyte is smaller than the RBC
Exflagellation
![](/.imaging/mte/default-theme/parasiteImage/dam/parasites/protozoa/malaria/plasmodium-vivax/P.vivax.Exflagellation.100x__006_001_004_006_002_002_002_00_.jpg/jcr:content/P.vivax.Exflagellation.100x__006_001_004_006_002_002_002_00_.jpg)
Exflagellation
- Under certain circumstances the microgametocyte of P. vivax can exflagellate in a thin film of human blood
- A process that normally takes place in the vector's gut
- There the microgamete (male) undergo a nuclear division and become motile to find and to penetrate the female macrogamete