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Schistosomiasis, intestinal
Pathology
  • Schistosomiasis is mainly an “immunological disease”
    In early infections one might observe:
    - Dermatitis (a reaction against invading cercariae)
    - Katayama fever (an acute syndrome against schistosomulae in the lungs)
    In chronic infections:
    - Granuloma formation around eggs deposited in tissues (mainly the liver) leading to hepatic portal fibrosis, portal hypertension and hepatosplenomegaly in heavy infections
  • Damage is also induced mechanically by eggs which migrate from blood vessels to the intestinal lumen (intestinal haemorrhage)

 

Sequelae of infection with Schistosoma spp.

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