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Fascioliasis Diagnosis
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Fascioliasis
Diagnosis

Diagnostic methods

Parasitological methods
Diagnosis is based on finding eggs in stools or in bile aspirated from the duodenum.
Passage of eggs can be detected temporarily after a meal with infected liver!
The diagnosis can be confined by serodiagnostic tests when available.

Molecular diagnosis

A PCR-RFLP assay has been developed for the distinction between F. hepatica and F. gigantica.

Antigen detection

No tests developed so far

Antibody detection
The newer serological assays (mainly ELISA formats) use recombinant or purified antigen (e.g. cathepsin L1)

 

Diagnostic strategies

To confirm the small number of human cases (in an outbreak), the optimal diagnostic strategy relies on (repeated) stool examinations combined with serology

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