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Diagnostic Methods
Diagnostic methodsPros and cons
Parasitological diagnosis 
Dracunculiasis is diagnosed clinically by the effect of the gravid female worm (blister, then skin ulcer) or by an abscess induced by a dying worm). The adult worm may be seen protruding from the skin lesion.
Calcified worms may be seen by X-ray.
Molecular diagnosis 
No tests developed 
Antigen detection 
Attempts to demonstrate D. medinensis antigens have so far been unsuccessful 
Antibody detection 
Immunodiagnostic tests have been explored using adult female worm and first-stage larval antigens. The most promising first results were obtained by detecting specific IgG4 antibodies.
  • Specificity of serologic test is not yet fully validated