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Clonorchiasis
Pathology
  • No early liver damage since young flukes ascend the biliary tree from the duodenum
  • Severity of the disease depends on the worm burden
  • Pathology is caused by mechanical damage and also by toxic effects of parasitic metabolites
  • The gall bladder might be enlarged in heavy infections
  • In heavy chronic infections, one might find fibrosis of the bile duct and periductal tissues
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